Faculty
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Faculty and Staff
Academicians
Faculty and Staff
 
Name:
Ye Yang
Education:
Ph.D

Positions:
Deputy director of Shanghai Institute of Materia Medica, Professor/Ph.D candidate supervisor, Principal Investigator
Academic title:
Professor
Phone:
021-50806067
Fax:
021-50807088
E-mail:
yye@mail.shcnc.ac.cn
Personal Website:
Postal Code:
201203
Mailing Address:
555 Zu Chong Zhi Road, Zhang Jiang Hi-Tech Park, Pudong, Shanghai, P.R.China
Resume:
Born in 1965, Yang Ye has got his Ph. D. in Shanghai Institute of Materia Medica, Chinese Academy of Sciences in 1992. He was an Alexander von Humboldt fellow and made his postdoctoral stay in the Institute of Organic Chemistry, University of Munich. Yang Ye is now a full professor and deputy director of Shanghai Institute of Materia Medica, Chinese Academy of Sciences. He is also in the editorial/advisory board of 7 international journals
and book series, including Planta Medica, Phytochemistry Letters, Progress in the Chemistry of Organic Natural Products, Chinese Medicine, etc.

Research Directions
Dr.Ye mainly focuses on the secondary metabolites in traditional
herbal medicinal plants and their bioactivities. Our goal is to disclose the chemical essence of traditional usages of Traditional Chinese Medicine and folk herbs, as well as to find potential pharmaceutical lead compounds by our isolation and structural modification approaches and collaborative work with pharmacological research groups.

Social Titles
Editors of Planta Medica,Phytochemistry Letters, Progress in the Chemistry of Organic Natural Products, China Pharmaceutical Almanac,etc

Awards & Honors
In 2008, the CAS-Bayer Award for young scientist. In 2007, the second prize of Shanghai Pharmaceutical Science and Technology.

Achievements

Grants & Research Projects
  1. Key New Drug Creation and Manufacturing Program supported by the National Science & Technology Major Project
  2. National Natural Science Funds for Distinguished Young Scholar(1.10.2009-30.09.2012)
  3. Study on the bioactive constituents of medicinal plants of Malvaceae family from Central Asia (01.01.2009-31.12.2011) supported by Bureau of International Co-operation of Chinese Academy of Sciences
  4. Studies on structural modification of paeoniflorin for curing stroke and lead compound(s) finding (01.01.2009-31.12.2011) supported by National Natural Science Foundation of China
  5. The anti-diabetic activities of natural components from TCM Momordica charantia (01.01.2008-31.12.2010) supported by National Natural Science Foundation of China
  6. Studies on the anti-diabetes structure activity relationship of cucurbitane triterpenoids and lead compound(s) finding.(01.09.2008-31.08.2011) supported by Science and Technology Commission of Shanghai Municipality
  7. Technology support program on shikimic acid and related secondary metabolites (01.01.2008-31.12.2009) supported by Ministry of Science and Technology

Pubilcations
  1. Min-Jia Tan, Ji-Ming Ye, Nigel Turner, Cordula Hohnen-Behrens, Chang-Qiang Ke, Chun-Ping Tang, Tong Chen, Hans-Christoph Weiss, Ernst-Rudolf Gesing, Alex Rowland, David E. James, and Yang Ye*, Antidiabetic activities of triterpenoids isolated from Bitter Melon associated with activation of the AMPK pathway, Chemistry & Biology, 2008, 15(3), 263-273. Impact factor: 6.52
  2. Li-Gen Lin, Hua Xie, Hong-Lin Li, Lin-Jiang Tong, Chun-Ping Tang, Chang-Qiang Ke, Qun-Fang Liu, Li-Ping Lin, Mei-Yu Geng, Hua-Liang Jiang, Wei-Min Zhao, Jian Ding, and Yang Ye*, Naturally Occurring Homoisoflavonoids Function as Potent Protein Tyrosine Kinase Inhibitors by c-Src-based High-Throughput Screening, Journal of Medicinal Chemistry, 2008, 51(15), 4419-4429. Impact factor: 4.895
  3. Liang Ma, Fan Ge, Chun-Ping Tang, Chang-Qiang Ke, Xi-Qiang Li, Andreas Althammer, Yang Ye*, The absolute configuration determination of naturally occurring diacetylenic spiroacetal enol ethers from Artemisia lactiflora, Tetrahedron, 2011, 67, 3533-3539. Impact factor: 3.219
  4. Qin Zhu, Chun-Ping Tang, Chang-Qiang Ke, Xi-Qiang Li, Jin Liu, Li-She Gan, Hans-Christoph Weiss, Ernst-Rudolf Gesing, and Yang Ye*, Constituents of Trigonostemon chinensis, Journal of Natural Products 2010, 73(1), 40-44. Impact factor: 3.159
  5. Yi Zhang, Chun-Ping Tang, Chang-Qiang Ke, Sheng Yao, and Yang Ye*, Limonoids and Triterpenoids from the Stem Bark of Melia toosendan, Journal of Natural Products 2010, 73(4), 664-668. Impact factor: 3.159