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  您现在的位置: 首页 > 研究队伍
姓    名:
蒋兴宇
性    别:
职    务:
纳米生物效应与安全性研究室副主任
职    称:
研究员
通讯地址:
北京市海淀区中关村北一条11号
邮政编码:
100190
电子邮件:
xingyujiang(AT)nanoctr.cn

 简历:
  蒋兴宇于1999年在美国芝加哥大学取得化学学士,于2004获得美国哈佛大学化学博士学位。其后在哈佛大学从事博士后研究。在哈佛期间师从George Whitesides。2005年开始在国家纳米科学中心工作,任研究员、博士生导师,入选中科院“百人计划”。 2010 年获得国家自然基金委员会杰出青年基金。
研究工作包括:1) 用有机化学、高分子材料、表面化学、和微纳米结构等技术控制蛋白质和细胞与固体表面的相互作用;并用这些技术来解决细胞在固体表面粘附、单个细胞在表面分化和移动的一些基本问题。模式组织的研究工作,在构建体外的多种细胞的培养体系。2) 用微流控来进行高通量的药物检测、高效的疾病诊断等。3) 非常规的方法制备微纳米结构及其生化应用。4)纳米颗粒在生化检测以及应对多药耐药革兰氏阴性菌的应用。
最近几年发表论文50多篇,共被引用2000多次。

 研究领域:
  纳米生物医学

 社会任职:
 

 获奖及荣誉:
 

 代表论著:
 

1. Using self-polymerized dopamine to modify the antifouling property of oligo(ethylene glycol) self-assembled monolayers and its application in cell patterning, Sun, K., Song, L., Xie, Y., Liu, D., Wang, D., Wang, Z., Ma, W., Zhu, J., Jiang, X.Y. Langmuir. 27, 5709-5712 (2011). pdf

2. Colorimetric detection of mercury, lead and copper ions simultaneously using protein-functionalized gold nanoparticles, Guo,Y., Wang, Z. , Qu, W., Shao, H. , Jiang, X.Y.  Biosens. Bioelectron., doi:10.1016/j.bios.2011.03.0332011 (2011).pdf 

3. Microfluidic devices constructed by a marker pen on a silica gel plate for multiplex assays, Fang, X., Chen, H., Jiang, X.Y., Kong, J. Anal. Chem. doi.org/10.1021/ac200024a (2011).pdf

4. Resettable, multi-readout logic gates based on controllably reversible aggregation of gold nanoparticles, Liu, D., Chen, W., Sun, K., Deng, K., Zhang, W., Wang, Z., Jiang, X.Y. Angew. Chem. Int. Ed. 50, 4103-4107 (2011).pdf

5. Copper-mediated amplification allows readout of immunoassays by the naked Eye, Qu,W., Liu, Y., Liu, D., Wang, Z, Jiang X.Y. Angew. Chem. Int. Ed. 50, 3442-3445 (2011).pdf

6. Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules, Liu, D., Wang, Z., Jiang, X.Y. Nanoscale, 3 (4), 1421 – 1433 (2011).pdf

7. Predicting viruses accurately by a multiplex microfluidic loop-mediated isothermal amplification chip, Fang X. E., Chen, H., Yu, S. N., Jiang, X. Y., Kong, J., Anal. Chem. 83 (3), 690–695 (2011).pdf

8. In vitro model on glass surfaces for complex interactions between different types of cells, Chen, Z.L., Zhang, W. , Jiang, X.Y.  et al, Langmuir, 26(23), 17790-17794 (2010).pdf

9. Highly sensitive, colorimetric detection of mercury(II) in aqueous media by quaternary ammonium group-capped gold nanoparticles at room temperature, Liu, D.B, Qu, W. S., Chen, W. W., Zhang, W., Wang, Z. , Jiang, X. Y. , Anal. Chem., 82(23), 9606-9610 (2010).pdf

10. A strategy for the modification of electrospun fibers that allows diverse functional groups for biomolecular entrapment, Chen, W., He, S., Pan, W.Y., Jin, Y., Zhang, W., Jiang, X.Y., Chem. Mater., 22(23),6212-6214 (2010).pdf

11. A simple design in PDMS-based microfluidic channels that rids bubbles in long-term on-chip culture of mammalian cells, Zheng, W.F., Wang, Z., Zhang, W., Jiang, X.Y., Lab Chip, 10, 2906-2910 (2010).

12. A general approach for patterning multiple types of cells using holey PDMS membranes and microfluidic channels, Yuan B., Li Y., Wang D., Xie Y., Liu Y., Cui L., Tu F., Li H., Ji H., Zhang W., Jiang X.Y. , Adv. Funct. Mater. 20, 3715-3720 (2010).pdf

13. Development of neurons on micropatterns reveals that growth cone responds to a sharp change of concentration of laminin, Xing, S.G., Liu, W.W., Huang, Z., Chen, L., Sun, K., Han, D., Zhang, W., Jiang, X.Y., Electrophoresis, 31, 3144-3151 (2010). pdf

14. Recent developments employing new materials for readout in lab-on-a-chip. Liu, Y.Y., Sun, Y., Sun, K., Song, L.S., and Jiang, X.Y., J. Mater. Chem., 20, 7305–7311 (2010). pdf

15. Small-molecule capped gold nanoparticles as potent antibacterial agents that target Gram-negative bacteria. Zhao, Y.Y., Tian, Y., Cui, Y., Liu, W.W, Ma, W.S. and Jiang, X.Y., J. Am. Chem. Soc., 132 (35), 12349–12356 (2010). pdf

16. Adsorbed Tween 80 is unique in its ability to improve the stability of gold nanoparticles in solutions of biomolecules. Zhao, Y.Y., Wang, Z., Zhang, W., Jiang, X.Y., Nanoscale, 2, 2114-2119 (2010). pdf

17. Enhanced exciton migration in electrospun poly[2-methoxy-5-(2'-ethylhexyloxy)-
1,4-phenylenevinylene]/poly(vinyl pyrrolidone) nanofibers. Zhou, R.T., Chen, W., Jiang, X.Y., Wang, S.F., Gong, Q.H., Appl. Phys. Lett., 96,133309 (2010).pdf 

18. Microfluidic Western Blot. Pan, W.Y., Chen, W., Jiang, X.Y., Anal. Chem., 82, 3974–3976 (2010). pdf

19. A stretching device for imaging real-time molecular dynamics of live cells adhering to elastic membranes on inverted microscopes during the entire process of the stretch. Wang, D., Xie, Y.Y., Yuan B., Xu J., Gong P.Y. and Jiang, X.Y., Integr. Biol., 2, 288–293 (2010).pdf 
 
20. Loop-Mediated isothermal amplification integrated on microfluidic chips for Point-of-Care quantitative detection of pathogens. Fang, X.E., Liu, Y.Y., Kong, J.L., Jiang, X.Y., Anal. Chem., 82 (7), 3002–3006 (2010). pdf

21. Fabrication of necklace-like structures via electrospinning. Jin, Y., Yang, D.Y., Kang, D.Y., Jiang, X.Y., Langmuir, 26(2), 1186-1190 (2010). pdf

22. Electrospinning of poly(dimethylsiloxane)/poly(methylmethacrylate) nanofibrous membrane: fabrication and application in protein microarrays. Yang, D.Y., Liu, X., Jin, Y., Zhu, Y., Zeng, D.D., Jiang, X.Y., Ma, H.W., Biomacromolecules, 10(12), 3335-3340 (2009). pdf

23. Patterning multiple types of mammalian cells for modeling three types of naturally occurring cell-cell interactions. Chen, Z.L., Li, Y., Liu, W.W., Zhang, D.Z., Zhao, Y.Y., Yuan, B., Jiang, X.Y., Angew. Chem. Int. Ed., 48(44), 8303-8305 (2009).pdf
 
24. Using azobenzene-embedded self-assembled monolayers to reversibly control cell adhesion. Liu, D.B., Xie, Y.Y., Shao, H.W., Jiang, X.Y., Angew. Chem. Int. Ed., 48(24), 4406-4408 (2009). pdf

25. Visual detection of copper(II) by azide- and alkyne-functionalized gold nanoparticles using click chemistry. Zhou, Y., Wang, S.X., Zhang, K., Jiang, X.Y., Angew. Chem. Int. Ed., 47 (39), 7454-7456 (2008).

26. Modular microfluidics for gradient generation. Sun, K., Wang, Z.X., Jiang, X.Y., Lab Chip, 8, 1536-1543 (2008). pdf

27. Electrospun nanofibrous membranes: a novel solid substrate for microfluidic immunoassays for HIV. Yang, D.Y., Niu, X., Liu, Y.Y., Wang, Y., Gu, X., Song, L.S., Zhao, R., Ma, L.Y., Shao, Y.M., Jiang X.Y., Adv. Mater., 20 (24), 4770-4775 (2008).pdf 

28. Fabrication of aligned fibrous arrays by magnetic electrospinning. Yang, D., Lu, B., Zhao, Y., Jiang, X.Y., Adv. Mater., 19(21), 3702-3706 (2007). pdf

29. A method for patterning multiple types of cells by using electrochemical desorption of self-assembled monolayers within microfluidic channels. Li, Y., Yuan, B., Ji, H., Han, D., Chen, S.Q., Tian, F., Jiang, X.Y., Angew. Chem. Int. Ed., 46(7), 1094-1096 (2007). pdf


 承担科研项目情况:
  国家863计划科技部973课题中科院“百人计划”