• ● Faculty and Staff
Guangjun Nie
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Mailing Address:
No.11,Beiyitiao Zhongguancun Beijing,china


Ph.D   Biophysics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 2002
M.S.   Biochemistry and Molecular Biology, Jilin University, China 1999
B.S.   Biology, Northeast Normal University, China 1996

Principal Investigator   National Centre for Nanoscience and Technology, China, Beijing 2008
Postdoctoral Associate  Jewish General Hospital, McGill University, Canada 2002-2008
Visiting Scholar       Institute of Food Research, Norwich, United Kingdom 06-12, 2000


1.Using nanotechnology to target and regulate tumors and their microenvironment for diagnostic and therapeutic applications
2.Novel biomaterials design and synthesis inspired by biomolecules
3.Cellular membrane vesicle systems and their roles in biological effects of nanomaterials
4.Regulation of blood cell differentiation and underlying molecular mechanisms of the related human disorders




Tianjiao Ji, Ying Zhao, Yanping Ding and Guangjun Nie, Using nanotechnology to target and regulate the tumor microenvironment: diagnostic and therapeutic applications, Advanced Materials, doi: 10.1002/adma.201300299.pdf

Yanping Ding, Suping Li & Guangjun Nie, Nanotechnological strategies for therapeutic targeting and imaging of tumor vasculature, Nanomedicine, doi:10.2217/NNM.13.106.

Xin Tian, Motao Zhu, Libo Du, Jing Wang, Zhenlin Fan, Jun Liu Yuliang Zhao and Guangjun Nie, Intrauterine inflammation alters size-dependent materno-fetal transfer of nanoparticles in murine pregnancy, Small, doi: 10.1002/smll.201300817.pdf

Tianjiao Ji, Ying Zhao, Jing Wang, Xin Zheng, Yanhua Tian, Yuliang Zhao and Guangjun Nie, Tumor fibroblast specific activation of hybrid ferritin nanocage-based optical probe for tumor microenvironment imaging, Small, doi: 10.1002/smll.201300600.

Shishuai Su, Hai Wang, Xiaoguang Liu, Yan Wu, Guangjun Nie, iRGD-coupled responsive fluorescent nanogel for targeted drug delivery, Biomaterials, 2013, 34, 3523-3533.pdf

Hai Wang, Yan Wu, Ruifang Zhao and Guangjun Nie, Engineering the assemblies of biomaterial nanocarriers for delivery of multiple theranostic agents with enhanced antitumor efficacy, Advanced Materials, 2013, 25, 1616-1622.pdf

Motao Zhu, Sarah, Perrett and Guangjun Nie, Understanding the Particokinetics of Engineered Nanomaterials for Safe and Effective Therapeutic Applications, Small, 2013, 9, 1619-34.pdf

Hui Yang, Cuiji Sun, Zhenlin Fan, Xin Tian, Liang Yan, Libo Du, Yang Liu, Chunying Chen, Xing-jie Liang, Gregory J. Anderson, Jeffrey A. Keelan, Yuliang Zhao, Guangjun Nie, Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy, Scientific Report, 2012, 847; DOI:10.1038/srep00847.pdf 

Wendi Zhang, Chi Wang, Zhenzhen Lu, Jun-Jie Yin, Yu-Ting Zhou, Xingfa Gao, Ying Fang, Guangjun Nie, Yuliang Zhao, Unraveling Stress-induced Toxicity Properties of Graphene Oxide and the Underlying Mechanism, Advanced Materials 2012, 24, 5391–5397.pdf

Motao Zhu, Xin Tian, Xiao Song, Yanhua Tian, Yuliang Zhao, and Guangjun Nie, Nanoparticle-Induced Exosomes Target Antigen-Presenting Cells to Initiate Th1-Type Immune Activation, Small, 2012, 24, 2841-2848.pdf

Gang Liu, Shiwen Niu, Ailian Dong, Hao Cai, Gregory J Anderson, Bing Han and Guangjun Nie, A Chinese family carrying novel mutations in the SEC23B and HFE2 genes, British Journal of Haematology, 2012, 158, 143-145.pdf

Xin Tian, Motao Zhu, Yanhua Tian, Ramm A. Grant, Yuliang Zhao, Guangjun Nie, A membrane vesicle-based dual vaccine against melanoma and Lewis lung carcinoma, Biomaterials, 2012, 33, 6147-6154.pdf

Motao Zhu, Yiye Li, Jian Shi, Weiyue Feng, Guangjun Nie, and Yuliang Zhao, Cellular Responses to Nanomaterials: Exosomes as Extrapulmonary Signaling Conveyors for Nanoparticle-Induced Systemic Immune Activation, Small, 2012, 8, 404-412.pdf

Bo Ning, Gang Liu, Yuanyuan Liu, Xiufen Su, Gregory J Anderson, Xin Zheng, Yanzhong Chang, Mingzhou Guo, Yuanfang Liu, Yuliang Zhao and Guangjun Nie, 5-aza-2'-deoxycytidine activates iron uptake and heme biosynthesis by increasing c-Myc nuclear localization and binding to the E-boxes of TfR1 and ferrochelatase genes, J Biol Chem, 2011, 286, 37196-37206.pdf

Hai Wang, Ying Zhao, Yan Wu, Kaihui Nan, Guangjun Nie and Hao Chen, Enhanced antitumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxyPEG-PLGA copolymer nanoparticles, Biomaterials, 2011, 32, 8281-8290.pdf

Yiye Li, Yunlong Zhou, Hai-Yan Wang, Sarah Perrett, Yuliang Zhao, Zhiyong Tang, Guangjun Nie, Chirality of Glutathione Surface Coating Affects the Toxicity of Quantum Dots, Angew Chem Int Ed, 2011, 50, 5860-5864.pdf

Cuiji Sun, Hui Yang,Yi Yuan, Xin Tian, Liming Wang, Yi Guo, Li Xu, Jianlin Lei, Ning Gao, Gregory J. Anderson, Xing-jie Liang, Chunying Chen, Yuliang Zhao, Guangjun Nie, Controlling assembly of paired gold clusters within apoferritin nanoreactor for in vivo kidney targeting and biomedical imaging, J Am Chem Soc, 2011, 133, 8617–8624.pdf

Jia Fan, Jun-Jie Yin, Bo Ning, Xiaochun Wu, Ye Hu, Mauro Ferrari, Gregory J. Anderson, Jingyan Wei, Yuliang Zhao and Guangjun Nie, Direct evidence for catalase and peroxidase activities of ferritin-platinum nanoparticles, Biomaterials, 2011, 32, 6, 1611-1618.pdf

Guangjun Nie, Guohua Chen, Alex D. Sheftel, Kostas Pantopoulos and Prem Ponka. In Vivo Tumor Growth is Inhibited by Cytosolic Iron Deprivation Caused by the Expression of Mitochondrial Ferritin, Blood, 2006, 108:2428-34.pdf

Guangjun Nie, Alex Sheftel, Songwon Kim, Prem Ponka. Overexpression of Mitochondrial Ferritin Causes Cytosolic Iron Depletion and Changes Cellular Iron Homeostasis. Blood, 2005, 105:2161-7.pdf

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