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Details of the Faculty or Staff
Name  
Yong-Gang Yao
Title  
 
Highest Education 
  Ph.D.
Address  
Kunming Institute of Zoology, the Chinese Academy of Sciences No. 32 Jiaochang Donglu, Kunming, Yunnan, 650223, P.R.China
Phone  
  +86 871 5180085
Zip Code  
  650223
Fax  
  +86 871 5180085
E-mail  
  ygyaozh@gmail.com

Education and Appointments:

Yong-Gang Yao, Ph.D., Professor
Tel/Fax: 86-871-5180085 (office); 86-871-5198969 (lab)
E-mail: ygyaozh@gmail.com or yaoyg@mail.kiz.ac.cn
2007.12 – Present:  Principal Investigator, Kunming Institute of Zoology, Chinese Academy of Sciences
2004.10 – 2008.01: Visiting Fellow, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health
2003.02 – 2004.09:  Postdoctoral Fellow, Wilmer Eye Institute, Johns Hopkins University School of Medicine
1997.09 – 2003.01: Ph. D., Kunming Institute of Zoology, Chinese Academy of Sciences.
2001.05 – 2001.08: Visiting Scholar, Fachbereich Mathematik, Universität Hamburg, Hamburg, Germany.
1997.09 –1998.07: Graduate School of the Chinese Academy of Sciences, Beijing
1993.09 –1997.07: B.S., Department of Biology, Anhui Normal University

Associate Editor, Journal of Human Genetics
Associate Editor, Zoological Research
Editorial Board, Journal of Genetics and Genomics


Research Interest:

Our laboratory focuses on understanding the genetic basis and molecular mechanisms of human disorders and aging. We are striving for EAF (E = Evolutionary analysis; A = Association study; F = Functional assay), Easy And Fun.

Public Services:

Honors:

1998  Dongshi Eastern Fellowship, Graduate School of the Chinese Academy of Sciences, Beijing.
2000  Di-Ao Scholarship and President Scholarship of the Chinese Academy of Sciences.
2001  Short-term fellowship from the German Deutscher Akademischer Austauschdienst (DAAD).
2002  Special President Scholarship for postgraduate students of the Chinese Academy of Sciences.
2003  Award for Science and Technology Advancement of Yunnan Province (third place). Awardees: Xue-Ping Li, Ya-Ping Zhang, Xiao-Yong Man, Yong-Gang Yao, Chang-Zhi Mao, Huai-Rong Luo, Jing-Fen Zheng; project title: Association of complement C4 null genes and C2 gene genotypes with systemic lupus erythematosus in southwest Han Chinese
2004  Award for Science and Technology Advancement of Yunnan Province (third place). Awardees: Lu-Ming Dai, Ya-Ping Zhang, Xin Lu, Yong-Gang Yao, Min Yang, Jian-Qing Zhang, Li-Zhou Fang; project title: ß2-adrenoceptor polymorphisms and asthma exacerbations
2005  The top 100 Ph.D. thesis of China. Thesis title: Demographic History of the Chinese Ethnic Groups: a Mitochondrial DNA Perspective
2006  State Natural Science Award of China (second place). Awardees: Ya-Ping Zhang, Yong-Gang Yao, Qing-Peng Kong, Yuan-Chun Ding, Chang Sun; project title: Mitochondrial genome diversity and population history of East Asian.

Selected Publication:

Peer-reviewed Publications and Comments (* corresponding author):
1.Fan L, Yao Y-G*. 2011. MitoTool: A web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11: 351-356
2.Kong Q-P, Sun C, Wang H-W, Zhao M, Wang W-Z, Zhong L, Hao X-D, Pan H, Wang S-Y, Cheng Y-T, Zhu C-L, Wu S-F, Liu L-N, Jin J-Q, Yao Y-G, Zhang Y-P. 2011. Large-scale mtDNA screening reveals a surprising matrilineal complexity in East Asia and its implications to the peopling of the region. Molecular Biology and Evolution, 28: 513-522
3.Peng M-S, Palanichamy MG, Yao Y-G, Mitra B, Cheng YT, Zhao M, Liu J, Wang H-W, Pan H, Wang W-Z, Zhang A-M, Zhang W, Wang D, Zou Y, Yang Y, Chaudhuri TK, Kong Q-P, Zhang Y-P. 2011. Inland post-glacial dispersal in East Asia revealed by mitochondrial haplogroup M9a'b. BMC Biology 9: 2 (doi: 10.1186/1741-7007-9-2.)
4.Wang Y, Zhu Q, Zhao XL, Yao Y-G, Liu Y-P. 2011. Age-related expression profile of the SLC27A1 gene in chicken tissues. Molecular Biology Reports, in press
5.Zhang W, Chen X*, Gong W, Tang J, Tan L, Guo H, Yao Y-G*. 2010. Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese. Behavioral and Brain Functions 6: 75 (doi:10.1186/1744-9081-6-75)
6.Yu D, Jia X, Zhang A-M, Li S, Zou Y, Zhang Q*, Yao Y-G*. 2010. Mitochondrial DNA sequence variation and haplogroup distribution in Chinese patients with LHON and m.14484T>C. PLoS ONE,  5(10): e13426
7.Chen S-Y, Liu Y-P, Yao Y-G*. 2010. Species authentication of commercial beef jerky based on PCR-RFLP analysis of the mitochondrial 12S rRNA gene. Journal of Genetics and Genomics 37: 763-769
8.Zou Y, Zeng Y, Zhang D-F, Zou S-H, Cheng Y-F*, Yao Y-G*. 2010. IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders. Biochemical and Biophysical Research Communications, 402: 378-383
9.Li Y-Y, Li X-A, He L, Qang D, Chen W-Y, Chen L, Lu J-B, Yao Y-G. 2010. Trends in new leprosy case detection over 57 years (1952-2008) in Yuxi, Yunnan Province of Southwest China. Leprosy Review, in press.
10.Bi R, Zhang A-M, Zhang W, Kong Q-P, Wu B-L, Yang X-H, Wang D, Zou Y, Zhang Y-P, Yao Y-G*. 2010. The acquisition of an inheritable 50-bp deletion in the human mtDNA control region does not affect the mtDNA copy number in peripheral blood cells. Human Mutation, 31: 538-543
11.Zou Y, Jia X, Zhang A-M, Wang W-Z, Li S, Guo X, Kong Q-P, Zhang Q*, Yao Y-G*. 2010. The MT-ND1 and MT-ND5 genes are mutational hotspots for Chinese families with clinical features of LHON but lacking the three primary mutations. Biochemical and Biophysical Research Communications, 399: 179-185
12.Zhang A-M, Jia X, Zhang Q*, Yao Y-G*. 2010. No association between the SNPs (rs3749446 and rs1402000) in the PARL gene and LHON in Chinese patients with m.11778G>A. Human Genetics, 128: 465-468
13.Bi R, Zhang A-M, Yu D, Chen D, Yao Y-G*. 2010. Screening the three LHON primary mutations in the general Chinese population by using an optimized multiplex allele-specific PCR. Clinica Chimica Acta, 411: 1671-1674
14.Peng M-S, Quang H-H, Dang K-P, Trieu A-V, Wang H-W, Yao Y-G, Kong Q-P, Zhang Y-P. 2010. Tracing the Austronesian footprint in mainland Southeast Asia: a perspective from mitochondrial DNA. Molecular Biology and Evolution, 27: 2417-2430
15.Yu D, Jia X, Zhang A-M, Guo X, Zhang Y-P, Zhang Q*, Yao Y-G*. 2010. Molecular characterization of six Chinese families with m.3460G>A and Leber hereditary optic neuropathy. Neurogenetics, 11: 349-356
16.Wang Y, Zhu Q, Zhao XL, Yao Y-G*, Liu Y-P*. 2010. Association of FATP1 gene polymorphisms with chicken carcass traits in Chinese meat-type quality chicken populations. Molecular Biology Reports, 37: 3683-3690
17.Kong Q-P, Bandelt H-J, Zhao M, Zhang Y-P, Yao Y-G. 2010. Reply to van Oven: Suggestions and caveats for naming mtDNA haplogroup. Proceedings of the National Academy of Sciences of the United States of America, 107: E40-E41 (doi:10.1073/pnas.1000977107; comment)
18.Wang Q, Wang P, Li S, Xiao X, Jia X, Guo X, Kong Q-P, Yao Y-G, Zhang Q. 2010. Mitochondrial DNA haplogroup distribution in Chaoshanese with and without myopia. Molecular Vision,  16: 303-309
19.Zhou B, Chen S-Y, Zhu Q, Yao Y-G, Liu Y-P. 2010. Matrilineal components and genetic relationship of Silkies from China and Japan. Journal of Poultry Science, 47: 22-27
20.Yao Y-G, Salas A, Logan I, Bandelt H-J. 2009. mtDNA data-mining in GenBank needs surveying. American Journal of Human Genetics, 85: 929-933
21.Zhao M, Kong Q-P, Wang H-W, Peng M-S, Xie X-D, Wang W-Z, Jiayang, Duan J-G, Cai M-C, Zhao S-N, Cidanpingcuo, Tu Y-Q, Wu SF, Yao Y-G, Bandelt H-J, Zhang Y-P. 2009. Mitochondrial genome evidence reveals successful Late Paleolithic settlement on the Tibetan Plateau. Proceedings of the National Academy of Sciences of the United States of America, 106: 21230-21235
22.Bandelt H-J, Salas A, Taylor RW, Yao Y-G*. 2009. The exaggerated status of "novel" and "pathogenic" mtDNA sequence variants due to inadequate database searches. Human Mutation, 30: 191-196
23.Zhang A-M, Zou Y, Guo X, Jia X, Zhang Q*, Yao Y-G*. 2009 Mitochondrial DNA mutation m.3635G>A may be associated with Leber hereditary optic neuropathy in Chinese. Biochemical and Biophysical Research Communications, 386: 392–395
24.Chen S-Y, Huang Y, Zhu Q, Fontanesi L, Yao Y-G*, Liu Y-P*. 2009. Sequence characterization of the MC1R gene in yak (Poephagus grunniens) breeds with different coat colours. Journal of Biomedicine and Biotechnology, Volume 2009, Article ID 861046; doi:10.1155/2009/861046
25.Zhang Z-R, Liu Y-P, Yao Y-G, Jiang X, Du H, Zhu Q. 2009. Identification and association of the single nucleotide polymorphisms in calpain3 (CAPN3) gene with carcass traits in chickens. BMC Genetics, 10: 10; doi:10.1186/1471-2156-10-10
26.Bandelt H-J, Yao Y-G, Bravi CM, Salas A, Kivisild T. 2009. Median network analysis of defectively sequenced entire mitochondrial genomes from early and contemporary disease studies. Journal of Human Genetics, 54:174-181
27.Liu Y-P, Cao S-X, Chen S-Y, Yao Y-G, Liu T-Z. 2009. Genetic diversity of Chinese domestic goat based on the mitochondrial DNA sequence variation. Journal of Animal Breeding and Genetics, 126: 80-89
28.Ji Y, Zhang A-M, Jia X, Zhang Y-P, Xiao X, Li S, Guo X, Bandelt H-J, Zhang Q, Yao Y-G*. 2008. Mitochondrial DNA haplogroups M7b1'2 and M8a affect clinical expression of Leber Hereditary Optic Neuropathy in Chinese families with the m.11778G→A mutation. American Journal of Human Genetics, 83: 760-768
29.Yao Y-G*, Kong Q-P, Salas A, Bandelt H-J. 2008. Pseudo-mitochondrial genome haunts disease studies. Journal of Medical Genetics, 45: 769-772
30.He D-Q, Zhu Q, Chen S-Y, Wang H-Y, Liu Y-P*, Yao Y-G*. 2008. A homogenous nature of Chinese native duck matrilineal pool. BMC Evolutionary Biology, 8: 298; doi:10.1186/1471-2148-8-298
31.Bandelt H-J, Yao Y-G, Richards M, Salas A. 2008. The brave new era of human genetic testing. BioEssays, 30: 1246-1251
32.Kong Q-P, Salas A, Sun C, Fuku N, Tanaka M, Zhong L, Wang C-Y, Yao Y-G, Bandelt H-J. 2008. Distilling artificial recombinants from large sets of complete mtDNA genomes. PLoS ONE, 3:e3016; doi:10.1371/journal.pone.0003016
33.Zhang A-M, Jia X, Yao Y-G*, Zhang Q*. 2008. Co-occurrence of A1555G and G11778A in a Chinese family with high penetrance of Leber's hereditary optic neuropathy. Biochemical and Biophysical Research Communications, 376: 221-224
34.Wang H-W, Jia X, Ji Y, Kong Q-P, Zhang Q*, Yao Y-G*, Zhang Y-P. 2008. Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 643: 48-53
35.Bandelt H-J, Yao Y-G, Salas A. 2008. The search of 'novel' mtDNA mutations in hypertrophic cardiomyopathy: MITOMAPping as a risk factor. International Journal of Cardiology, 126: 439-442
36.Chen S-Y, Liu Y-P, Wang W, Gao C-Z, Yao Y-G, Lai S-J. 2008. Dissecting the matrilineal components of Tongjiang cattle from southwest China. Biochemical Genetics, 46: 206-215
37.Ji Y, Jia X, Zhang Q, Yao Y-G. 2007. mtDNA haplogroup distribution in Chinese patients with Leber’s hereditary optic neuropathy and G11778A mutation. Biochemical and Biophysical Research Communications, 364: 238-242
38.Wu G-S, Yao Y-G, Qu K-X, Ding Z-L, Li H, Palanichamy Mg, Duan Z-Y, Li N, Chen Y-S, Zhang Y-P. 2007. Population phylogenomic analysis of mitochondrial DNA in wild boars and domestic pigs revealed multiple domestication events in East Asia. Genome Biology, 8:R245;  doi:10.1186/gb-2007-8-11-r245
39.Yao Y-G*, Childs RW, Kajigaya S, McCoy JP, Jr, Young NS. 2007. Mitochondrial DNA sequence heterogeneity of single CD34+ cells after nonmyeloablative allogeneic stem cell transplantation. Stem Cells, 25:2670-2676
40.Yao Y-G*, Bandelt H-J, Young NS. 2007. External contamination in single cell mtDNA analysis. PLoS ONE, 2: e681; doi:10.1371/journal.pone.0000681
41.Wang C-Y, Wang H-W, Yao Y-G, Kong Q-P, Zhang Y-P. 2007. Somatic mutations of mitochondrial genome in early stage breast cancer. International Journal of Cancer, 121: 1253-1256
42.Bandelt H-J, Olivieri A, Bravi C, Yao Y-G, Torroni A, Salas A. 2007. ‘Distorted’ mitochondrial DNA sequences in schizophrenic patients. European Journal of Human Genetics, 15: 400-402
43.Yao Y-G*, Ogasawara Y, Kajigaya S, Molldrem JJ, Falcão RP, Pintão M-C, McCoy JC, Jr, Rizzatti EG, Young NS. 2007. Mitochondrial DNA sequence variation in single cells from leukemia patients. Blood, 109: 756-762
44.Yao Y-G*, Ellison FM, McCoy JP, Jr, Chen J, Young NS. 2007. Age-dependent accumulation of mtDNA mutations in murine hematopoietic stem cells is modulated by the nuclear genetic background. Human Molecular Genetics, 16: 286-294
45.Lai S-J, Chen S-Y, Liu Y-P, Yao Y-G. 2007. Mitochondrial DNA sequence diversity and origin of Chinese domestic yak. Animal Genetics, 38: 77-80
46.Bandelt H-J, Yao Y-G, Salas A, Kivisild T, Bravi CM. 2007. High penetrance of sequencing errors and interpretative shortcomings in mtDNA sequence analysis of LHON patients. Biochemical and Biophysical Research Communications, 352: 283-291)
47.Wang C-Y, Kong Q-P, Yao Y-G*, Zhang Y-P. 2006. MtDNA mutation C1494T, haplogroup A, and hearing loss in Chinese. Biochemical and Biophysical Research Communications, 348: 712-715
48.Man X-Y, Yang X-H, Cai S-Q, Yao Y-G, Zheng M. 2006. Immunolocalization and expression of vascular endothelial growth factor receptors (VEGFRs) and neuropilins (NRPs) on keratinocytes in human epidermis. Molecular Medicine, 12: 127-136
49.Yang X-H, Man X-Y, Cai S-Q, Yao Y-G, Bu Z-Y, Zheng M. 2006. Expression of VEGFR-2 on HaCaT cells is regulated by VEGF and plays an active role in mediating VEGF induced effects. Biochemical and Biophysical Research Communications, 349: 31-38
50.Kong Q-P, Bandelt H-J, Sun C, Yao Y-G, Salas A, Achilli A, Wang C-Y, Zhong L, Zhu C-L, Wu S-F, Torroni A, Zhang Y-P. 2006. Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations. Human Molecular Genetics, 15: 2076-2086
51.Yao Y-G*, Salas A, Bravi CM, Bandelt H-J. 2006. A reappraisal of complete mtDNA variation in East Asian families with hearing impairment. Human Genetics, 119: 505-515
52.Salas A, Yao Y-G, Bandelt H-J. 2006. Mitochondria: more than mitochondrial DNA in cancer - author’s reply. PLoS Medicine, 3: e166; doi:10.1371/journal.pmed.0030166 (comment)
53.Sun C, Kong Q-P, Palanichamy MG, Agrawal S, Bandelt H-J, Yao Y-G, Khan F, Zhu C-L, Chaudhuri TK, Zhang Y-P. 2006. The dazzling array of basal branches in the mtDNA macrohaplogroup M from India as inferred from complete genomes. Molecular Biology and Evolution, 23: 683-690
54.Palanichamy MG, Agrawal S, Yao Y-G, Kong Q-P, Sun C, Khan F, Chaudhuri TK, Zhang Y-P. 2006. Comment on ‘‘Reconstructing the origin of Andaman islanders’’. Science, 311: 470; doi: 10.1126/science.1120176 (comment)
55.Liu Y-P, Zhu Q, Yao Y-G*. 2006. Genetic relationship of Chinese and Japanese gamecocks revealed by mtDNA sequence variation. Biochemical Genetics, 44: 19-29
56.Liu Y-P, Wu G-S, Yao Y-G, Miao Y-W, Luikart G, Baig M, Beja-Pereira A, Ding Z-L, Palanichamy MG, Zeng F-T, Qiu X-P, Zhang Y-P. 2006. Multiple maternal origins of chickens: out of the Asian jungles? Molecular Phylogenetics and Evolution, 38: 12-19
57.Lai S-J, Liu Y-P*, Liu Y-X, Li X-W, Yao Y-G*. 2006. Genetic diversity and origin of Chinese cattle revealed by mtDNA D-loop sequence variation. Molecular Phylogenetics and Evolution, 38: 146-154
58.Salas A, Yao Y-G, Macaulay V, Vega A, Carracedo A, Bandelt H-J. 2005. A critical reassessment of the role of mitochondria in tumorigenesis. PLoS Medicine, 2: e296; doi:10.1371/journal.pmed.0020296
59.Bandelt H-J, Achilli A, Kong Q-P, Salas A, Lutz-Bonengel S, Sun C, Zhang Y-P, Torroni A, Yao Y-G. 2005. Low “penetrance” of phylogenetic knowledge in mitochondrial disease studies. Biochemical and Biophysical Research Communications, 333: 122-130
60.Yao Y-G, Yang HS, Cao Z, Danielsson J, Duh EJ. 2005. Upregulation of placental growth factor by vascular endothelial growth factor via a post-transcriptional mechanism. FEBS Letters, 579: 1227-1234
61.Bandelt H-J, Yao Y-G, Kivisild T. 2005. Mitochondrial genes and schizophrenia. Schizophrenia Research, 72: 267-269
62.Yao Y-G, Kong Q-P, Wang C-Y, Zhu C-L, Zhang Y-P. 2004. Different matrilineal contributions to genetic structure of ethnic populations in Silk-Road region in China. Molecular Biology and Evolution, 21: 2265-2280
63.Yao Y-G, Duh EJ. 2004. VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis? Biochemical and Biophysical Research Communications, 321: 648-656
64.Yao Y-G, Bravi CM, Bandelt H-J. 2004. A call for mtDNA data quality control in forensic science. Forensic Science International, 141: 1-6
65.Kong Q-P, Yao Y-G, Sun C, Zhu C-L, Zhong L, Wang C-Y, Cai W-W, Xu X-M, Xu A-L, Zhang Y-P. 2004. Phylogeographic analysis of mitochondrial DNA haplogroup F2 in China reveals T12338C in the initiation codon of the ND5 gene not to be pathogenic. Journal of Human Genetics, 49: 414-423
66.Duh EJ, Yao Y-G, Dagli M, Goldberg MF. 2004. Persistence of fetal vasculature in a patient with Knobloch Syndrome: potential role for endostatin in fetal vascular remodeling of the eye. Ophthalmology, 111: 1885-1888
67.Luan Y-X, Yao Y-G, Xie R-D, Yang Y-M, Zhang Y-P, Yin W-Y. 2004. Analysis of 18S rRNA gene of Octostigma sinensis (Projapygoidea: Octostigmatidae) supports the monophyly of Diplura. Pedobiologia, 48: 453-459
68.Yao Y-G*, Macaulay V, Kivisild T, Zhang Y-P, Bandelt H-J. 2003. To trust or not to trust an idiosyncratic mitochondrial data set. American Journal of Human Genetics, 72: 1341-1346
69.Yao Y-G*, Macaulay V, Kivisild T, Zhang Y-P, Bandelt H-J. 2003. Mitochondrial DNA variation in Amerindians - Reply to Silva et al. American Journal of Human Genetics, 72: 1348-1349 (Comment)
70.Yao Y-G, Zhang Y-P. 2003. Pitfalls in the analysis of ancient human mtDNA. Chinese Science Bulletin, 48: 826-830
71.Yao Y-G, Kong Q-P, Sun C, Zhang Y-P. 2003. Can the occurrence of rare insertion/deletion polymorphisms in human mtDNA be verified from phylogeny? Chinese Science Bulletin, 48: 663-667
72.Yao Y-G, Kong Q-P, Man X-Y, Bandelt H-J, Zhang Y-P. 2003. Reconstructing the evolutionary history of China: a caveat about inferences drawn from ancient DNA. Molecular Biology and Evolution, 20: 214-219
73.Kong Q-P, Yao Y-G, Liu M, Chen C, Zhu C-L, Palanichamy MG, Zhang Y-P. 2003. Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China. Human Genetics, 113: 391-405
74.Kong Q-P, Yao Y-G, Sun C, Bandelt H-J, Zhu C-L, Zhang Y-P. 2003. Phylogeny of East Asian mitochondrial DNA lineages inferred from complete sequences. American Journal of Human Genetics, 73: 671-676
75.Bandelt H-J, Herrnstadt C, Yao Y-G, Kong Q-P, Kivisild T, Rengo C, Scozzari R, Richards M, Villems R, Macaulay V, Howell N, Torroni A, Zhang Y-P. 2003. Identification of Native American founder mtDNAs through the analysis of complete mtDNA sequences: some caveats. Annals of Human Genetics, 67: 512-524
76.Kong Q-P, Yao Y-G, Huang S-Y, Huang J-F, Zhang Y-P. 2003. Mitochondrial DNA control region and cytochrome b sequence variation in the genus Mystacoleucus Günther (Pisces: Cyprinidae: Barbinae) from China. Biochemical Genetics, 41: 305-313
77.Man X-Y, Luo H-R, Li X-P, Yao Y-G, Mao C-Z, Zhang Y-P. 2003. Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese. Annals of the Rheumatic Diseases, 62: 71-73
78.Yao Y-G, Kong Q-P, Bandelt H-J, Kivisild T, Zhang Y-P. 2002. Phylogeographic differentiation of mitochondrial DNA in Han Chinese. American Journal of Human Genetics, 70: 635-651
79.Yao Y-G, Nie L, Harpending H, Fu Y-X, Yuan Z-G, Zhang Y-P. 2002. Genetic relationship of Chinese ethnic populations revealed by mtDNA sequence diversity. American Journal of Physical Anthropology, 118: 63-76
80.Yao Y-G, Zhang Y-P. 2002. Phylogeographic analysis of mtDNA variation in four ethnic populations from Yunnan Province: new data and a reappraisal. Journal of Human Genetics, 47: 311-318
81.Yao Y-G, Kong Q-P, Zhang Y-P. 2002. Mitochondrial DNA 5178A polymorphism and longevity. Human Genetics, 111: 462-463
82.Luo H-R, Lü X-M, Yao Y-G, Horie N, Takeishi K, Jorde LB, Zhang Y-P. 2002. Length polymorphism of thymidylate synthase regulatory region in Chinese populations and evolution of the novel alleles. Biochemical Genetics, 40: 41-51
83.Zhang Y-W, Fang Y-H, Long H-S, Yao Y-G, Cai Q, Zhang Y-P. 2002. Sequence variation of rbcL gene and evolution of Saccharum and related species. Acta Botanica Yunnanica, 24: 29-36 (In English with Chinese abstract)
84.Yao Y-G, Yuan Z-G, Zhou Z-D, Geng P-L, Li Q-W, Zhang Y-P. 2001. Frequency of the mtDNA 9-bp deletion in Chinese ethnic groups. Progress in Natural Science, 11: 358-364
85.Yang Z-Q, Zuo Y-X, Yao Y-G, Chen X-W, Yang G-C, Zhang Y-P. 2001. Analysis of the 18S rRNA genes of Sarcocystis species suggests that the morphologically similar organism from cattle and water buffalo should be considered the same species. Molecular and Biochemical Parasitology, 115: 283-288
86.Yao Y-G, Kong Q-P, Zhang Y-P. 2001. Methods and thoughts on detecting nucleotide variation in human mitochondrial DNA. Zoological Research 22: 321-331 (In Chinese)
87.Yuan Z-G, Yao Y-G, Ma Z-X, Pang Q-P, Jie Y-R, Ma J, Zhang Y-P. 2001. Mitochondrial DNA sequence variations of Zhuang ethnic group in Guangxi. Acta Genetica Sinica, 28:95-102 (In Chinese)
88.Yu Y-S, Yao Y-G, Kong Q-P, Rong J-Q, Luo Z-G, Ren G-X, Zhang Y-P. 2001. Mitochondrial DNA sequence variations of Shui ethnic group. Acta Genetica Sinica, 28: 691-698 (In Chinese)
89.Yao Y-G, Watkins WS, Zhang Y-P. 2000. Evolutionary history of the mtDNA 9-bp deletion in Chinese populations and its relevance to the peopling of East and Southeast Asia. Human Genetics, 107: 504-512
90.Yao Y-G, Lü X-M, Luo H-R, Li W-H, Zhang Y-P. 2000. Gene admixture in the silk road of China: evidence from mtDNA and melanocortin 1 receptor polymorphism. Genes & Genetic Systems, 75: 173-178
91.Ding Y-C, Wooding S, Harpending H, Chi H-C, Li H-P, Fu Y-X, Pang J-F, Yao Y-G, Xiang YJG, Moyzis R, Zhang Y-P. 2000. Population structure and history in East Asia. Proceedings of the National Academy of Sciences of the United States of America, 97: 14003-14006
92.Yao Y-G, Zhang Y-P. 2000. Mitochondrial DNA and human evolution. Zoological Research 21: 392-406 (In Chinese)
93.Zhou J-L, Yao Y-G, Huang M-H, Yang D-T, Lü S-Q, Zhang Y-P. 2000. Phylogenetic relationships among Viperidae, Crotalinae based on mitochondrial 12S rRNA sequence variations. Acta Genetica Sinica 27: 283-289 (In Chinese)


Supported Projects:
Our laboratory focuses on understanding the genetic basis and molecular mechanisms of human disorders and aging. We are striving for EAF (E = Evolutionary analysis; A = Association study; F = Functional assay), Easy And Fun.
Current research has four major concentrations:
1. onset risk factors and pathogenesis of leprosy, Leber's hereditary optic neuropathy and schizophrenia
2. mitochondrial and nuclear gene mutations in major degenerative disorders and tumorigenesis
3. Biology of Chinese tree shrews
4. the identification of genes and/or genetic variants that are associated with specific traits in domestic animals
In addition, students in Yao lab are encouraged to develop their own interdisciplinary projects.