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姓 名: |
高云华 |
性 别: |
女 |
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职 务: |
无 |
职 称: |
研究员 |
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学 历: |
博士 |
通讯地址: |
无 |
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电 话: |
82543581 |
邮政编码: |
无 |
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传 真: |
无 |
电子邮件: |
yhgao@mail.ipc.ac.cn |
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主 页: |
无 |
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| 简历： |
| 高云华 女，1987年于北京师范大学化学系毕业。1989年7月赴日本朝日大学从事访问研究，1990年转入日本冈山大学攻读学位，1996年3月获得博士学位。1996年东京都立大学博士后，1998年至2000年底在日本冈山大学自然科学研究科VBL(Venture Business Lab)任讲师，2000年入选中国科学院“百人计划”，2001年回国工作。现任中国科学院理化技术研究所研究员，博士生导师。 |
| 研究领域： |
| 主要研究方向是生物芯片/生物传感器高灵敏高通量快速检测技术平台的研究以及新型经皮给药系统的研究。 |
| 代表论著： |
| 近期论文： 1) Microneedle Array for Transdermal Drug Delivery: Studies on Delivery Parameters and Biocompatibility，Yan Wu, Suohui Zhang, Yuqin Qiu, Guangjiong Qin and Yunhua Gao1*, Biomedical microdevices (in press). 2) Enhancement of skin permeation of docetaxel by a combination of microneedle pretreatment and elastic liposomes，Yuqin Qiu, Yunhua Gao1*, Kejia Hu, Fang Li , J. controlled release,(in press). 3）Synthesis, characterization and photochromic studies of three novel calix[4]arene–Schiff bases, Zhi Liang , Zhilian Liu , Yunhua Gao,* Spectrochimica Acta Part A , 2007, 68, 1231–1235 4) A new fluorescent chemosensor for copper(II) and molecular switch controlled by light, Zhi Liang, Zhilian Liu, Lin Jiang and Yunhua Gao,*Tetrahedron Letters , 2007, 48, 1629–1632 5) A selective colorimetric chemosensor based on calixarene framework for lanthanide ions-Dy3+ and Er3+, Zhi Liang, Zhilian Liu and Yunhua Gao,* Tetrahedron Letters, 2007, 48, 3587–3590 6) Functionalization of chitosan with 3,4-dihydroxybenzoic acid for the adsorption/collection of uranium in water samples and its determination by inductively coupled plasma-mass spectrometry，Akhmad Sabarudin, Mitsuko Oshima, Toshio Takayanagi, Lukman Hakim, Koji Oshita, Yun Hua Gao and Shoji Motomizu, Analytica Chimica Acta, 2007, 214-220 7）Sequential-injection on-line preconcentration using chitosan resin functionalized with 2-amino-5-hydroxy benzoic acid for the determination of trace elements in environmental water samples by inductively coupled plasma-atomic emission spectrometry, Akhmad Sabarudin , Narong Lenghor , Mitsuko Oshima, Lukman Hakim, Toshio Takayanagi , Yun-Hua Gaob, Shoji Motomizua* Talanta, 2007,72, 1609–1617 8） A selective colorimetric chemosensor for lanthanide ions, Zh. Liu, L. Jiang, Zh. Liang and Y. Gao*, Tetrahedron, 2006, 62 ,3214–3220 9） Modeling of transdermal drug delivery with a microneedle array, Y-G Lv, J Liu, Y-H Gao and B Xu, J. Micromech. Microeng. 2006, 16,1–10 10) Photochromism of a novel spiropyran derivative based on calix[4]arenas, Zhilian Liu, Lin Jiang, Zhi Liang, Yunhua Gao*, J. Mol. Struct, 2005, 737, 267-270. 11) Magnetically-Actuated Micromixing on Array-Pattern Microfluidic Chip for Immunoassay of TSH，Chengwu Li, Yongning Wang, Yunhua Gao*, XiaoYing Guo and Zhongze Gu， Journal of Nanoscience and Nanotechnology. 2005，1297-1300. 12) An Artificial Aspartic Proteinase System, Lin Jiang, Zhilian Liu, Zhi Liang, and Yunhua Gao*, Bioorganic & Medicinal Chemistry, 2005, 13, 3673-80. 13) Photo-switching molecular devices based on metal-ionic recognition, Zhilian Liu, Lin Jiang , Zhi Liang and Yunhua Gao*, Tetrahedron Letters, 2005, 46,885-887. 14) Controlled transdermal delivery of model drug compounds by MEMS microneedle array，Yu Xie1, Bai Xu2*, Yunhua Gao1*, Nanomedicine, 2005, 1,184. |
| 承担科研项目情况： |
| 在研项目： 1) “863”计划先进制造技术领域：“新型CMOS生物传感器集成技术研究” 2) 科技部支撑计划课题“出入境检验检疫安全储备技术研究” 3) 中科院创新方向性项目：“抗肿瘤纳米药物微针透皮释药研究” 4) 中科院仪器设备研制和改造项目：“BioMEMS基片快速成型系统的研制” 企业合作项目3项 |
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