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姓  名:
彭景楩
学  科:
发育生物学
电话/传真:
+86-10-64807183 / 
电子邮件:
pengjp@ioz.ac.cn
通讯地址:
北京市朝阳区北辰西路1号院5号
中国科学院动物研究所 计划生育生殖生物学国家重点实验室 100101
更多信息:
生殖免疫研究组  
简历:

  彭景楩,男,1958年1月出生于湖北武汉市,博士,研究员,博士生导师;新世纪百千万人才工程国家级人选,发育与生殖重大研究项目首席科学家。计划生育生殖生物学国家重点实验室副主任,生殖免疫组组长。
  1996年毕业于中国农业大学生物学院,获理学博士学位。96年4月-98年11月在美国Georgetown大学医学中心和Rutgers大学完成二项博士后研究。2000年4 -12月在Rutgers大学作合作研究。主要从事生殖分子免疫学领域的研究,研究兴趣主要集中在:1)妊娠过程中母胎识别与免疫豁免的分子表达及调控机制;以生殖免疫调控基因和相关因子为切入点,探索母-胎免疫耐受机制;2)基因疫苗机理与应用的研究:研究免疫控制生育、免疫抗生殖系统肿瘤的分子机理。03年、06年两次获国家人口和计划生育科技工作先进个人荣誉称号;2004年荣获“中央国家机关五一劳动奖章”荣誉称号,享受国务院政府特殊津贴。近10年来,发表论文55篇,其中在SCI源期刊发表论文38篇;获国家发明专利5项。参编学术著作国内外各一部;申报受理国家发明专利2项。

研究领域:
社会任职:
获奖及荣誉:
承担科研项目情况:
  • 973项目(2006CB504006):滋养层侵入的分子基础与肿瘤侵润
  • 重大科学研究计划项目(2006CB944007):母胎免疫豁免和排斥的分子机理
  • 国家自然基金面上项目(30770246):CYP26A1在大鼠胚胎植入中的作用及其分子机理的研究
代表论著:
  1. Gao-Feng Xiong, Yan-Shuai Zhang, Bing-Chen Han, Wen Chen, Ying Yang, Jing-Pian Peng*(2011). Estradiol-regulated gene praline-rich acid protein 1 repressed by class I histone deacetylase and its action in peri-implantation mouse uterus. Mol Cell Endocrinol. 331: 23-33 
  2. Hong Fei-Xia, Jing-Jing Ma, Jing Sun, Ying Yang, Jing-Pian Peng*(2010). Retinoic acid metabolizing enzyme CYP26A1 is implicated in rat embryo implantation Hum Reprod, 25(12):2985-2998
  3. Wen Chen, Bing-Chen Han, Rong-Chun Wang, Gao-Feng Xiong, Jing-Pian Peng*, (2010)The role of secretory protease inhibitor SPINK3 in mouse uterus during early pregnancy. Cell Tissue Res 341: 441-451.
  4. Bing-Chen Han, Hong Fei-Xia, Jing Sun, YingYang, Jing-Pian Peng*, (2010) Retinoic Acid-Metabolizing Enzyme Cytochrome P450 26a1 (Cyp26a1) Is Essential for Implantation: Functional Study of Its Role in Early Pregnancy. J. Cell. Physiol. 223:471–479.
  5. Hong Fei-Xia,  Jing Sun, Quan-Hong Sun, Ying Yang, Jing-Pian Peng*(2008) Implantation associated gene-1 (Iag-1): a novel gene involved in the early process of embryonic implantation in rat. Hum Reprod, 23(7):1581–1593.
  6. Li Xu; Shu-Qun Shi; Ying Yang; Jing-Pian Peng* (2007) Researches on four cDNA fragments from rabbit ZP3: their immunogenicity and effects on fertility, Fertil and Steril. 87(2):381-390.
  7. Shu-Qun Shi, Li Xu, Gang Zhao, Yang Ying, Jing-Pian Peng*,(2006) Apoptosis and tumor inhibition induced by human chorionic gonadotropin beta in mouse breast carcinoma. J Mol Medi.-jmm. 84:933–941
  8. Jian-Jun Chang,6. Jing-Pian Peng* YingYang, Jing-LingWang, LiXu (2006) Study on the Anti-fertility Effects of the Plasmid DNA Vaccine Expressing Partial brLDH-C4. Reprod. 131: 183–192.  
  9. Quan-Hong Sun, Jing-Pian Peng*, Hong-Fei Xia, (2005)  Effect on expression of RT1-A and RT1-DM molecules treatment with interferon gamma at the maternal-fetal interface of pregnant rat. Hum Reprod, 20(9):2639-2647.
  10. Ruo-lan Xiang, Fei Zhou, Ying Yang and Jing-pian Peng*,2. (2003)Construction of the Plasmid pCMV4-rZPC` DNA Vaccine and Analysis of its Contraceptive Potential,3. Biol Reprod, 68(5):1578-1524.
  11. Jing Sun, Hong-Fei Xia, YingYang, Jing-Pian Peng,*(2008) The antifertility effects of DNA vaccine-induced immune responses against uroguanylin. Vaccine. online on june, 2008) 
  12. Hong-Fei Xia,? Jing Sun, Quan-Hong Sun, Ying Yang, Jing-Pian Peng*(2008) Implantation associated gene-1 (Iag-1): a novel gene involved in the early process of embryonic implantation in rat. Human Reproduction. 23(7): 1581-1593.
  13. Quan-Hong Sun ?Jing-Pian Peng* Hong-Fei Xia Ying Yang, (2007) Interferon gamma promote apoptosis of uterus and placenta in pregnant rat and human cytotrophoblast cells. Journal of Interferon & Cytokine Research. 27: 567-578.
  14. Hong-Fei Xia, Quan-Hong Sun and Jing-Pian Peng,* (2007) Effect of interferon-g treatment on the expression of interleukin-1b at the maternal–fetal interface of pregnant rats. Reproduction, Fertility and Development. 19, 510–519.
  15. Li Xu, Shu-Qun Shi, Ying Yang, Jing-Pian Peng*, (2007) Researches on four cDNA fragments from rabbit ZP3: their immunogenicity and effects on fertility, Fertility and Sterility. 87(2):381-390.
  16. Shu-Qun Shi, Li Xu, Gang Zhao, Yang Ying, Jing-Pian Peng*,(2006) Apoptosis and tumor inhibition induced by human chorionic gonadotropin beta in mouse breast carcinoma. Journal of Molecular Medicine.-jmm. 84:933–941.
  17. Gang Zhao, Shu-Qun Shi, Ying Yang, and Jing-Pian Peng,* (2006) M and N proteins of SARS coronavirus induce apoptosis in HPF cells. Cell Biol Toxicol 22: 313–322.
  18. Hong-Fei Xia, Jing-Pian Peng *, Quan-Hong Sun , Ying Yang , and Mei-Ling Liu, (2006) Effects of IL-1 beta on RT1-A/RT1-DM at the maternal-fetal interface during pregnancy in rats. Frontiers in Bioscience. 11, 2868-2875.
  19. Shu-Qun Shi, Jing-PianPeng,*Yin-Chuan Li, Chuan Qin, Guo-Dong Liang, Li Xu, YingYang, Jin-LingWang, Quan-Hong Sun, (2006) The expression of membrane protein augments the specific responses induced by SARS-CoV nucleocapsid DNA immunization. Mol Immunol. 43(11):1791-1798.
写给考生的话:

  本人主要从事生殖分子免疫学领域的研究,研究兴趣主要集中在:1)妊娠过程中母胎识别与免疫豁免的分子表达及调控机制; 2)基因疫苗机理与应用的研究:研究免疫控制生育、免疫抗生殖系统肿瘤的分子机理。
  如果您对我所从事的研究方向感兴趣,真诚欢迎您报考。几多耕耘,几分收获,期盼我们在未来的3-5年中一起努力工作,不断求索,将我们组的研究工作推向一个新高度,我们期盼你的加入!