Location: Home > Scientists
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Name:
 MENG, An-Ming
Subject:
 Cell Biology
Tel/Fax:
 +86-10-64807213  /  +86-10-64807099
E-mail:
 mengam@ioz.ac.cn
Address:
 State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Siences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
More:
 Group of Developmental Signaling   
Resume:

Anming Meng Ph.D
Professor, Member of Chinese Academy of Sciences, director of Institute of Zoology, Chinese Academy of Sciences.
Recipient of the National Science Foundation of Outstanding Young Scientists of China in 2000
Outstanding Young Scholars (Biomedicine), sponsored by Qiu Shi Science & Technologies Foundation, Hong Kong, in 2000
Cheung Kong Scholar of the Ministry of Education of China in 2001
Prize for Science and Technology Advancement in 2007, awarded by the Ho Leung Ho Lee Foundation

1979-1983, Undergraduate of Southwestern Agricultural University.
1987-1990, PhD student of University of Nottingham, UK.
1990-1996, Postdoctoral fellow and associate professor of Beijing Agricultural University.
1996-1998, Visiting scholar of Medical College of Georgia.
1998 to now, Professor of Tsinghua University.
2008, Professor of Institute of Zoology, Chinese Academy of Sciences.

Research Interests:

Awards and Honors:

Professional Activities:

Research Grants:

Selected Publications:
  1. Zhao L, Zhao XY, Tian T, Lu QL, Skrbo-Larssen N, Wu D, Kuang Z, Zheng XF, Han YC, Yang SY, Zhang CM, Meng AM. 2008. Heart-specific isoform of tropomyosin4 is essential for heartbeat in zebrafish embryos. Cardiovascular Research, 80(2):200-8
  2. Meng FW, Cheng X, Yang LL, Hou N, Yang X, Meng AM. 2008. Accelerated re-epithelialization in Dpr2-deficient mice is associated with enhanced response to TGF-b signaling. Journal of Cell Science, 121(17):2904-12
  3. Jia SJ, Ren Z, Li X, Zheng Y, Meng AM. 2008. smad2 and smad3 are required for mesendoderm induction by TGF-b/Nodal signals in zebrafish. Journal of Biological Chemistry, 283(4):2418-2426.
  4. Lu ZL, Liu W, Huang HZ, He Y, Han Y, Wang YH, Li QX, Ruan K, Ye ZY, Low BC, Meng AM, Lin SC. 2008. Protein encoded by the AxinFu allele effectively downregulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signaling. Journal of Biological Chemistry, 283(19):13132-131329.
  5. Huang HZ, Lu F-I, Jia SJ, Meng S, Cao Y, Wang YQ, Ma WP, Yin K, Wen ZL, Peng JR, Thisse C, Thisse B, Meng AM. 2007. Amotl2 is essential for cell movements in zebrafish embryo and regulates c-Src translocation. Development, 134(5): 979-988.
  6. Su Y, Zhang L, Gao X, Meng FW, Wen J, Zhou H, Meng AM, Chen YG. 2007. The evolutionally conserved activity of Dapper2 in antagonizing TGFbeta signaling. The FASEB Journal, 21(3):682-690.
  7. Rui RY, Xu Z, Xiong B, Cao Y, Lin SY, Zhang M, Chan SC, Luo W, Han Y, Lu ZL, Ye ZY, Zhou HM, Han JH, Meng AM, Sheng-Cai Lin. 2007. A b-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by Aida. Developmental Cell, 13(2):268-282.
  8. Ma ACh, Lin R, Chan PK, Leung JC, Chan LY, Meng A, Verfaillie CM, Liang R, Leung AY. 2007. The role of survivin in angiogenesis during zebrafish embryonic development. BMC Developmental Biology, 7:50.
  9. Zhang S, Fei T, Zhang L, Zhang R, Chen F, Ning Y, Han Y, Feng XH, Meng A, Chen YG. 2007. Smad7 antagonizes TGF-b signaling in the nucleus by interfering with functional Smad-DNA complex formation. Mol Cell Biol., 27(12):4488-4499.
  10. Jia SJ, Meng AM. 2007. Tob genes in development and homeostasis. Developmental Dynamics, 236(4):913-921.
  11. Xiong B, Rui YN, Zhang M, Shi KH, Jia SJ, Tian T, Yin K, Huang HZ, Lin SY, Zhao XG, Chen YH, Chen Y-G, Lin S-C, Meng AM. 2006. Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal b-Catenin transcriptional activity. Developmental Cell，11：225-238.
  12. Lin X, Duan XY, Liang Y-Y, Su Y, Wrighton KH, Long JY, Hu M, Davis CM, Wang JR, Brunicardi FCB, Shi YG, Chen Y-G, Meng AM, Feng X-H. 2006. PPM1A functions as a Smad phosphatase to terminate TGFb signaling. Cell, 125(5):915-928.
  13. Sun ZH, Jin P, Tian T, Gu Y, Chen Y-G, Meng AM. 2006. Activation and roles of ALK4/ALK7-mediated maternal TGFb signals in zebrafish embryo. Biochem Biophys Res Commun., 345(2):694-703.
  14. Tian T, Meng AM. 2006. Nodal signals pattern vertebrate embryos.Cell Mol Life Sci., 63(6):672-685.
  15. Zhao CT, Meng AM. 2005. Sp1-like transcription factors are regulators of embryonic development in vertebrates. Development Growth & Differentiation，47:201-211.
  16. Zhang L, Zhou H, Su Y, Sun Z, Zhang H, Zhang L, Zhang Y, Ning Y, Chen Y-G, Meng AM. 2004. Zebrafish Dpr2 inhibits mesoderm induction by promoting lysosomal degradation of Nodal receptors. Science, 306(5693):114-117.
  17. Meng AM, Moore B, Tang H, Yuan BZ and Lin S. 1999. Drosophila doublesex-related gene, terra, is involved in somitogenesis in vertebrates. Development, 126:1259-1268.?
  18. Meng A, Tang H, Yuan BZ, Ong BA, Long Q, Lin S. 1999. Positive and negative cis-acting elements are required for hematopoietic expression of zebrafish GATA-1. Blood, 93(2):500-508.
  19. Meng A, Jessen J, Lin S. 1999. Transgenesis. Methods in Cell Biology, 60: 133-148.
  20. Meng AM, Tang H, Ong BA, Farrell MJ, Lin S. 1997. Promoter analysis in living zebrafish embryos identifies a cis-acting motif required for neuronal expression of GATA-2. Proc. Natl. Acad. Sci. USA, 94:6267-6272.