简历 & 研究组工作摘要：
        1955年毕业于中山大学
        1960年苏联科学院元素有机化合物研究所研究生毕业，获副博士学位
        1965-1967年英国皇家研究所及牛津大学访问学者
        1980年选为中国科学院院士
        1985年选为第三世界科学院院士
        现为中国科学院生物物理研究所研究员, 博士生导师。《中国科学》副主编，中国科学技术大学、华南师范大学兼职教授。

        60年代初测定了一批有机化合物晶体结构并与协作单位一起建立了我国第一个用于晶体结构分析的计算程序库。60年代末作为负责人之一参加了猪胰岛素晶体结构的测定。80年代初开始，主持胰岛素三维结构与功能研究，多项研究成果达到国际先进水平。90年代在一些生物酶分子以及在藻类捕光系统——藻胆蛋白色素复合物三维结构与功能研究上取得了重要结果。近些年来，积极推动并参与我国结构基因组学研究。己发表自然科学论文140余篇，专著《X射线晶体学基础》等。研究成果分别获1982年国家自然科学二等奖、1989年国家自然科学二等奖、1987年中国科学院自然科学一等奖及1986年、1992年中国科学院自然科学二等奖。1992年获首届王丹萍科学奖金，1995年获何梁何利科学与技术进步奖，2004年获北京市科学技术奖一等奖。

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Biography & Introduction

Liang Dong-Cai, Professor, Member of Chinese Academy of Sciences. Male, born in 1932. Liang graduated from the Department of Chemistry of Zhongshan University in 1955 and earned his doctor's degree in the Institute of Organo-Element Compounds, USSR Academy of Sciences, Moscow, in 1960. From 1965 to 1967, Liang serves as visiting scholar in Royal Institution and Oxford University in UK. He was elected as a member of Chinese Academy of Sciences in 1980 and a fellow of the Third World Academy of Sciences in 1985. Liang is presently a investigator and also a mentor of Ph. D students of the Institute of Biophysics, Chinese Academy of Sciences.

In early 1960s, Prof. Liang solved a series of crystal structures of organic compounds and established the first computational program library for crystal structure analysis in China. In the end of 1960s, Liang served as one of the chief scientists in charge of the research project on the crystal structure determination of porcine insulin. Since 1980, he has been taking charge in the research group on three-dimensional structure and function of insulin. Numerous world-leading results have been achieved. In the 1990's, he obtained important results on the research of the 3-D structure and function of light-harvesting system of algae, the phycobiliproteins. In recent years, he actively promotes and takes part in the research project of structural genomics in China.

Liang has ever published over 140 research articles in natural science and a specialized book named "The Basis of X-ray Crystallography"

Awards: Chinese National Scientific Prize, Second Rank, 1982; Scientific Prize of Chinese Academy of Sciences, First Rank,1987 and Second Ranks, 1986 and 1992; Chinese National Scientific Prize, Second Rank, 1989; Wang Danping  Science Award, 1992; 《Ho Leung Ho Lee》Prize,1994. Scientific and Technological Prize of Beijing, First Rank, 2004.

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Selected Publications：

Liang Shi, Jun-Feng Liu, Xiao-Min An, and Dong-Cai Liang; Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) from Thermoanaerobacter tengcongensis, a metal ion-dependent enzyme: Insight into the catalytic mechanism; PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATIS (in press)

Wang Yao, Liang Shi, Dong-Cai Liang ; Crystal structure of scaffolding protein CheW from thermoanaerobacter tengcongensis; BBRC 361 (2007) 1027-1032

Jun-Feng Liu, Zhan-Xin Wang, Xin-Quan Wang, Qun Tang, Xiao-Min An,Lu-Lu Gui, Dong-Cai Liang* ; Crystal structure of human dynein light chain Dnlc2A: Structural insights into the interaction with IC74; BBRC 349 (2006) 1125-1129

Cai-Hong Yun, Juan Bai, Da-Ye Sun, Da-Fu Cui, Wen-Rui Chang  and Dong-Cai Liang . Structure of potato calmodulin PCM6: the first report of the three-dimensional structure of a plant calmodulin. ACTA CRYSTALLOGR D 60, 1214-1219 (2004).

Xinquan Wang, Xiangyuan He, Shoujun Yang, Xiaomin An, Wenrui Chang and Dongcai Liang . Structural Basis for Thermostability of b -Glycosidase from the Thermophilic Eubacterium Thermus nonproteolyticus HG102. J BACTERIOL 185, 4248–4255 (2003).

Ming-Hui Li, Francis Kowk, Wen-Rui Chang, Chi-Kong Lau, Ji-Ping Zhang, Samuel C. L. Lo, Tao Jiang and Dong-Cai Liang . Crystal structure of brain pyridoxal kinase, a novel member of the ribokinase superfamily. J BIOL CHEM 277 (48), 46385-46390 (2002).

Tao Jiang, Ji-ping Zhang, Wen-rui Chang and Dong-cai Liang . Crystal Structure of R-phycocyanin and Possible Energy Transfer Pathways in the Phycobilisome. BIOPHYS J 81, 1171-1179 (2001).

Su-jin Bao, Dian-lin Xie, Ji-ping Zhang, Wen-rui Chang, and Dong-cai Liang . Crystal Structure of Desheptapeptide (B24-30) insulin at 1.6 angstrom Resolution: Implications for receptor binding. PROC NAT ACAD SCI USA 94, 2975-2980 (1997).