|
专家类别: 院士,杰出青年,百人计划,研究员
简历 & 研究组工作摘要: 1988年 中国科学院生物物理研究所获博士学位。 1989-1993年 在美国康乃尔大学和北达科他州立大学从事博士后研究。 1993年 回国任生物物理研究所研究员至今。 1997年当选为中国科学院院士。 现任清华大学生物科学与技术系教授。任中国生物物理学会常务理事,北京市生物化学学会副理事长,《中国科学》杂志编委,北京市学位委员会委员,第九届全国政协委员。
主要研究蛋白质物理化学、酶活性调节动力学、蛋白-配体相互作用、蛋白质结构预测。在SCI收录的期刊发表论文70篇。
请访问我的个人网站 >>>
Biography & Introduction
1988, Ph.D. Institute of Biophysics, Academia Sinica 1989-1993, Postdoctoral associate, Cornell University and North Dakota State University, USA 1993- Professor, Institute of Biophysics, Academia Sinica
I have published more than 70 papers in biochemistry and structural biology, and my present research interests center on the physical chemistry of protein, kinetics of enzyme catalysis and regulation, protein-ligand interaction and prediction of protein three-dimensional structure.
Visit my Group Page Here >>>
Selected Publications:
Wang ZX, Wu JW The complete pathway for ERK2-catalyzed reaction - Evidence for an iso random BiBi mechanism. J BIOL CHEM, 2007, 282(38): 27678-27684
Liu, J.H. & Wang Z.X. Kinetic analysis of ligand-induced autocatalytic reactions. BIOCHEM J 379, 597-702 (2004).
Wu, H. & Wang Z.X. The mechanism of p21-activated protein kinase 2 autoactivation. J BIOL CHEM 278, 41768-41778 (2003).
Wu, H., Zheng, Y. & Wang, Z.X. Evaluation of the catalytic mechanism of the p21-activated protein kinase PAK2. BIOCHEMISTRY-US 42, 1129-1139 (2003).
Wang, Z.X. and Wu, J.W. Autophosphorylation kinetics of protein kinases. BIOCHEM J 368, 947-952 (2002).
Wang, Z.X. & Yuan, Z. How good is the prediction of protein structural classes by the component-coupled method. Proteins 38, 165-175 (2000).
|