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  Location: Home >> Faculty >> Molecular Agrobiology
  Molecular Agrobiology

Hongqing Ling

1982 Bachelor of agronomy, Agricultural University of Sichuan, China
1988 Dipl.-Ing.agr. Christian-Albrechts-University of Kiel, Germany
1993 PhD Christian-Albrechts-University of Kiel, Germany


1982-1984 Assistant, Agricultural University of Sichuan, China,
1991-1992 Assistant, Christian-Albrechts-University of Kiel, China
1993-1997 Research staff, Institute of Plant Genetics and Crop Plant Research, Germany
1998-2001 Research staff, Institute of Plant Biology, University Zurich, Switzerland
2001-present Principle investigator, Institute of Genetics and Developmental Biology, CAS, China
Since 2006 10 Head of the State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, CAS, China


Molecular biology of plant nutrition
Molecular biology of plant resistance

Key publications
1. Li, Y., H. Wu, T. Zhao, H.-Q. Ling. Characterization of the AtSXP3 promoter elucidates its complex regulation in response to phosphorus deficiency. Plant & Cell Physiology 57: 1767-1778 (2016)
2. Yang, K., Z. Tian, C. Chen, L. Luo, B. Zhao, Z. Wang, L. Yu, Y. Li, Y. Sun, W. Li, Y. Chen, Y. Li, Y. Zhang, D. Ai, J. Zhao, C. Shang, Y. Ma, B. Wu, M. Wang, L. Gao, D. Sun, P. Zhang, F. Guo, W. Wang, Y. Li, J. Wang, R.K. Varshney, J. Wang, H.-Q. Ling, P. Wan. Genome sequencing of adzuki bean (Vigna angularis) provides insight into high starch and low fat accumulation and domestication. Proc. Natl. Acad. Sci. USA 112: 13213-13218 (2015)
3. Zamioudis, C., J. Korteland, J. Van Pelt, M. Van Hamersveld, N. Dombrowski, Y. Bai, J. Hanson, M. Van Verk, H.-Q. Ling, P. Schulze-Lefert, C. Pieterse. Rhizobacterial volatiles and photosynthesis-related signals coordinate MYB72 in Arabidopsis roots during onset of induced systemic resistance and iron deficiency responses. The Plant Journal 84: 309-322 (2015)
4. Du, J., Z. Huang, B. Wang, H. Sun, C. Chen, H.-Q. Ling and H. Wu. SlbHLH068 interacts with FER to regulate the iron-deficiency response in tomato. Annals of Botany 116: 23-34 (2015).
5. Sun, H., F.-J. Fan, H.-Q. Ling. Genome-wide identification and characterization of the bHLH gene family in tomato. BMC Genomics 16:9 (2015)
6. Zhang, Y., H.L. Wu, N. Wang, J. Fan, C.L. Chen, Y. Cui, H.F. Liu, H.-Q. Ling. Mediator subunit 16 functions in the regulation of iron uptake gene expression in Arabidopsis. New Phytologist 203: 770-783 (2014).
7. Fan, H.J., Z.L. Zhang, N. Wang, Y. Cui, H. Sun, Y. Liu, H.L. Wu, S.S. Zheng, S.L. Bao, H.-Q. Ling. SKB1/PRMT5-mediated histone H4R3 dimethylation of Ib subgroup bHLH genes negatively regulates iron homeostasis in Arabidopsis thaliana. The Plant Journal 77: 209-221 (2014)
8. Long, W.B., Y. Li, W.J. Zhou, H.-Q. Ling, S.S. Zheng. Sequence-based SSR marker development and their application in defining the introgressions of LA0716 (Solanum pennellii) in the background of cv. M82 (Solanum lycopersicum). PLoS ONE 8(12): e81091 (2013)
9. Kong, D.Y., C.L. Chen, H.L. Wu, Y. Li, J.M. Li, H.-Q. Ling. Sequence diversity and enzyme activity of ferric-chelate reductase LeFRO1 in tomato. Journal of Genetics and Genomics 40: 565-573 (2013)
10. Ling H.-Q., S. Zhao, D. Liu, J. Wang, H. Sun, C. Zhang, H. Fan, D. Li, L. Dong, Y. Tao, C. Gao, H. Wu., Y. Li, Y. Cui, X. Guo, S. Zheng, B. Wang, K. Yu, Q. Liang, W. Yang, X. Lou, J. Chen, M. Feng, J. Jian, X. Zhang, G. Luo, Y. Jiang, J. Liu, Z. Wang, Y. Sha, B. Zhang, H. Wu, D. Tang, Q. Shen, P. Xue, S. Zou, X. Wang, X. Liu, F. Wang, Y. Yang, X. An, Z. Dong, K. Zhang, X. Zhang, M.-C. Luo, J. Dvorak, Y. Tong, Ji. Wang, H. Yang, Z. Li, D. Wang, A. Zhang, Ju. Wang. Draft genome of the wheat A-genome progenitor Triticum urartu. Nature 496: 87-90 (2013).
11. Wang N., Cui Y., Liu Y., Fan H., Du J., Huang Z., Yuan Y., Wu H., Ling H.-Q. Requirement and functional redundancy of Ib subgroup bHLH proteins for iron deficiency responses and uptake in Arabidopsis thaliana. Molecular Plant 6: 503-513 (2013)
12. Du J., D. Zeng, B. Wang, Q. Qian, S. Zheng, H.-Q. Ling. Environmental effects on mineral accumulation in rice grains and identification of ecological specific QTLs. Environmental Geochemistry and Health 30: 161-170 (2013)
13. The Tomato Consortium. The tomato genome sequence provides insight into fleshy fruit evolution. Nature 485: 635-641 (2012)
14. Huang Z.-A., T. Zhao, H.-J. Fan, N. Wang, S.-S. Zheng, H.-Q. Ling. The upregulation of NtAN2 expression at low temperature is required for anthocyanin accumulation in juvenile leaves of Lc-transgenic tobacco (Nicotiana tabacum L.). Journal of Genetics and Genomics 39: 149-156 (2012)
15. Wu H., C. Chen, J. Du, H. Liu, Y. Cui, Y. Zhang, Y. He, Y. Wang, C. Chu, Z. Feng, J. Li, H.-Q. Ling. Co-overexpression FIT with AtbHLH38 or AtbHLH39 in Arabidopsis enhanced cadmium tolerance via increased cadmium sequestration in roots and improved iron homeostasis of shoots. Plant Physiology 158: 790-800 (2012)
16. Zhao, W., X. Cheng, Z. Huang, H. Fan, H. Wu, H.-Q. Ling: Tomato LeTHIC is a Fe-required HMP-P synthase involved in thiamine synthesis and regulated by multiple factors. Plant and Cell Physiology 52(6): 967-982 (2011)
17. Zhao, N., S. Zheng, H.-Q. Ling: An efficient regeneration system and Agrobacterium-mediated transformation of Chinese upland rice cultivar Handao297. Plant Cell Tissue and Organ Culture 106: 475-483 (2011)
18. Dong, L., X. Zhang, D. Liu, H. Fan, J. Sun, Z. Zhang, H. Qin, B. Li, S. Hao, Z. Li, D. Wang, A. Zhang, H.-Q. Ling: New insight into the organization, recombination, expression and functional mechanism of low molecular weight glutenin subunit genes in bread wheat. PLoS ONE 5(10): e13548. doi:10.1371/journal.pone.0013548 (2010)
19. Wu, H., Y. Ji, J. Du, D. Kong, H. Liang, H.-Q. Ling: ClpC1, an ATP-dependent Clp protease in plastids, is involved in iron homeostasis in Arabidopsis leaves. Annals of Botany 105: 823-833 (2010)
20. Ma, J.F., H.-Q. Ling: Iron for plants and humans. Plants and Soil 325: 1-3 (2009)
21. Cheng, X., D. Zhang, Z. Cheng, B. Keller, H.-Q. Ling: A new family of Ty1-copia-like retrotransposons originated in the tomato genome by a recent horizontal transfer event. Genetics 181: 1183-1193 (2009)
22. Ling, H.-Q., J. Du, N. Wang: Progress in understanding the molecular regulation of iron uptake in strategy I plants. In: Development and Uses of Biofortified Agricultural products, ed by Gary S.Banuelos and Zhi-Qing Lin. CRC press, Taylor & Francis Group. Pp 221-229.
23. Li, J., X.D. Wu, S.-T. Hao, X.J. Wang, H.-Q. Ling: Proteomic response to iron deficiency in tomato root. Proteomics 8, 2299-2311 (2008)
24. Kong, D., Y. Zhu, H. Wu, X. Cheng, H. Liang, H.-Q. Ling: AtTHIC, a gene involved in thiamine biosynthesis in Arabidopsis thaliana. Cell Research 18, 566-576 (2008).
25. Yuan, Y., H. Wu, N. Wang, J. Li, W. Zhao, J. Du, D. Wang, H.-Q. Ling: FIT interacts with AtbHLH38 and AtbHLH39 in regulating iron uptake gene expression for iron homeostasis in Arabidopsis. Cell Research 18, 385-397 (2008)
26. Bauer, P., H.-Q. Ling, M.L. Guerinot: FIT, the FER-LIKE IRON DEFICIENCY INDUCED TRANSCRIPTION FACOR in Arabidopsis. Plant Physiology and Biochemistry 45: 260-261 (2007)
27. Qiu J-W, Schuerch A, Yahiaoui N, Dong L, Fan H, Zhang Z, Keller B, Ling H-Q: Physical mapping and identification of a candidate for the leaf rust resistance gene Lr1 of wheat. Theoretical Applied Genetics 115: 159-168 (2007)
28. Zhao, T., H.-Q. Ling: Effects of pH and nitrogen forms on expression profiles of genes involved in iron homeostasis in tomato. Plant, Cell & Environment 30: 518-527 (2007)
29. Zhang, J., H.-F. Zhu, H. Liang, K.-F. Liu, A.-M., Zhang, H.-Q. Ling, D.-W. Wang: Further analysis of the function of AtbHLH29 in regulating the iron uptake process in Arabidopsis thaliana. Journal of Integrative Plant Biology 48(1): 75-84 (2006)
30. Wu, H., L. Li, J. Du, Y. Yuan, X. Cheng, H.-Q. Ling: Molecular and biochemical characterization of Fe(III)-chelate reductase gene family in Arabidopsis thaliana. Plant and Cell Physiology 46 (9): 1505-1514 (2005)
31. Yuan, Y.X, J. Zhang, D.W. Wang, H.-Q. Ling: AtbHLH29 of Arabidopsis thaliana is a functional ortholog of tomato FER involved in controlling iron acquisition in strategy I plants. Cell Research 15(8): 613-621 (2005)
32. Guyot, R., X. Cheng, Y. Su, Z. Cheng, E. Schlagenhauf, B. Keller, H.-Q. Ling: Complex organization and evolution of the tomato pericentromeric region at the FER gene locus. Plant Physiology 138: 1205-1215 (2005)
33. Li, L., X. Cheng, H.-Q. Ling: Isolation and characterization of Fe(III)-chelate reductase gene LeFRO1 in tomato. Plant Molecular Biology 54: 125-136 (2004)
34. Ling, H.-Q., J. Qiu, R.P. Singh, B. Keller: Identification and genetic characterization of an Aegilops tauschii ortholog of the wheat leaf rust disease resistance gene Lr1. Theoretical Applied Genetics 109: 1133-1138 (2004)
35. Ling, H.-Q., Y.X. Zhu and B. Keller: High-resolution mapping of the leaf rust disease resistance gene Lr1 in wheat and physical walking to the gene using a BAC library of Aegilops tauschii. Theoretical Applied Genetics 106: 875-882 (2003)
36. Ling, H.-Q., and B. Keller: Genetic transformation of Linum species. In: Plant Genetic Engineering Vol 4: Improvement of Commercial Plants-II. Ed by Pawan K Jaiwal and Rana P. Singh. Sci Tech Publishing LLC, U.S.A. pp235-260 (2003)
37. Ling, H.-Q., P. Bauer, B. Keller, M. Ganal: The fer gene encoding a bHLH transcriptional regulator controls development and physiology in response to iron in tomato. Proc. Natl. Acad. Sci. USA, vol. 99, 13938-13943 (2002)
38. Ling, H.-Q. and M. W. Ganal: Towards map-based cloning of two genes involved in iron uptake of tomato. Journal of Plant Nutrition 23: 1953-1967 (2000).
39. Ling, H.-Q., G. Koch, H. Baeumlein, M. W. Ganal: Map-based cloning of chloronerva – a gene involved in iron uptake of higher plants encoding nicotianamine synthase. Proc. Natl. Acad. Sci. USA, Vol. 96, 7098-7103 (1999)