严江伟----中国科学院北京基因组研究所

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·中国科学院
·中华人民共和国卫生部
·北京市科学技术委员会
·国家自然科学基金委员会
·中华人民共和国科学技术部

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副研究员

严江伟 ( Jiangwei Yan )
职称:	副研究员
职务:	科技处副处长
E-Mail:	yanjw@big.ac.cn
研究方向:	人类遗传多样性

简历：
	1992.09—1997.07西安医科大学获医学学士学位 2000.09—2003.11西安交通大学获医学硕士学位 2004.09—2007.07中国科学院北京基因组所获遗传学博士学位 1997.08—2007.12 北京市公安局法医鉴定中心DNA实验室副主任，副研究员 2008.01—至今中科院北京基因组研究所科技处副处长副研究员

主要研究领域：
	通过对现代及古代中国不同人群的遗传多样性以及相关的分析方法的研究，为中国人群的起源、疾病相关基因诊断和法医鉴定方面的应用提供分子生物学基础。

代表论著：

Zhu B, Shen C, Wang H, Yang G, Yan J, Qin HX, et al. Genetic diversities of 21 non-CODIS autosomal STRs of a Chinese Tibetan ethnic minority group in Lhasa. Int J Legal Med. 2010 Nov 3. [Epub ahead of print]

Zhu B, Shen C, Deng Y, Ye S, Yan J, Yang G, et al. Allele polymorphism and haplotype diversity of HLA-A, -B and -DRB1 loci in sequence-based typing for Chinese Uyghur ethnic group. PLoS ONE, 2010. 5(11): e13458.

Ge J, Eisenberg A, Yan J, Chakraborty R, Budowle B. Pedigree likelihood ratio for lineage markers. Int J Legal Med, 2010 Sep 21. [Epub ahead of print]

Ge J, Yan J, Budowle B, Chakraborty R, Eisenberg A. Issues on China forensic DNA database. Chinese Journal of Forensic Medicine, 2010.(Accepted)

Liu T, Bao Y, Yan J, et al. Molecular genetic analysis of the mtDNA A1555G mutation in patients with non-syndromic hearing loss. J Otolaryngol Ophthal Shandong UNI, 2009, 23(1), 40-43.

Wang Y, Yan J*, Shi Y，et al. Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection. BMC Infectious Diseases, 2009, 9:51.

Tang H, Liu Y, Yan J, Liu Y. Haplotypes of mtDNA control region in Yao ethnic from China. Forensic Sci Int: Genetics, 2008, Vol (1), 298-300.

Zhu B, Yan J*, et al. Population genetic analysis of 15 STR loci of Chinese Tu ethnic minority group, Forensic Sci Int, 2008, 174:255-258.

Guo H, Yan J*, et al. Genetic polymorphisms for 17 Y-chromosomal STRs haplotypes in Chinese Hui population. Leg Med (Tokyo), 2008, vol (10), 163-169.

Yan J, Liu Y, Tang H, Ma W, L Y, … , Yu J. Allele frequencies of mitochondrial D-loop (CA)n repeat polymorphism in six Chinese ethnic groups, Leg Med (Tokyo), vol(9) 2007,330-331.

Yan J, Tang H, Liu Y, Jing Y, Jiao Z, Zhang Q, Gao J. and Yu J. Whole Genome Amplification for Typing LCN and degraded DNA samples, Chinese Journal of Forensic Medicine, 2007, 22(2), 3-6.

Zhao X, Zhang Z, Yan J*, and Yu J. GC content variability of eubacteria is governed by the pol III alpha subunit, Biochem Biophys Res Commun, 2007, 356(1): 20-25.

Yan J, Zhao X, Li Y, Yu X, Xiong X, Mu H, Huang Y, Deng Y, Yu J. Genetic analysis of 15 STR loci on Chinese Tibetan in Qinghai Province, Forensic Sci Int, 2007, 169(1):e3-6.

Yan J, Tang H, Liu Y, Jing Y, Jiao Z, Zhang Q, Gao J, Shang L, Guo H, and Yu J. Genetic polymorphisms of 17 Y-STRs haplotypes in Chinese Han population residing in Shandong province of China, Leg Med (Tokyo), 2007,9(4):196-202.

Zhu B, Shen C, Xun X, Yan J, Deng Y, Zhu J, Liu, Y. Population genetic polymorphisms for 17 Y-chromosomal STRs haplotypes of Chinese Salar ethnic minority group, Leg Med (Tokyo) , 2007, Jul;9(4):203-9.

Zhang Q, Yan J, Jiao Z, … , and Liu Y. A tracking detection on chimerism after allogeneic hematopoietic stem cell transplantation, J Fourth Mil Med Univ, 2007, 28(6):534-6.

Yan J, Liu Y, Tang H, Zhang Q, Huo Z, Hu S. and Yu J. Mutations at 17 STR loci in Chinese population, Forensic Sci Int, 2006, 162(1-3):53-4.